/* ==========================================================================
   NuView Life Sciences — Global Stylesheet
   --------------------------------------------------------------------------
   HOW TO EDIT:
   - All brand colors, fonts and spacing live in :root below. Change them once
     here and the whole site updates.
   - Sections are grouped and labelled. Search for "SECTION:" to jump around.
   ========================================================================== */

/* --------------------------------------------------------------------------
   SECTION: Design Tokens (brand colors, type, spacing)
   Brand palette is taken from the existing nuviewlifesciences.com site:
   orange accent + deep navy + white. Tweak the hex values to fine-tune.
   -------------------------------------------------------------------------- */
:root {
  /* Brand colors */
  --orange:        #F26522;   /* primary accent (logo orange) */
  --orange-dark:   #D9551A;   /* hover / pressed */
  --orange-soft:   #FCE9DD;   /* soft tint backgrounds */
  --navy:          #0F2A3F;   /* primary dark / headings */
  --navy-deep:     #0A1E2D;   /* darkest sections / footer */
  --navy-700:      #18394F;

  /* Neutrals */
  --ink:           #16242E;   /* body text */
  --slate:         #51626E;   /* muted text */
  --line:          #E2E8EE;   /* borders / dividers */
  --page:          #EEF3F7;   /* soft tinted page background (base) */
  --mist:          #E4ECF2;   /* slightly deeper tint for alternating sections */
  --white:         #FFFFFF;

  /* Copper (Targeted Copper Theranostics accent — Cu-64 / Cu-67) */
  --copper:        #B87333;
  --copper-light:  #D89A5B;
  --copper-deep:   #8C5524;

  /* Functional */
  --ok:            #2E9E6B;
  --shadow-sm: 0 4px 16px rgba(15, 42, 63, .07);
  --shadow-md: 0 14px 34px rgba(15, 42, 63, .10);
  --shadow-lg: 0 30px 60px rgba(15, 42, 63, .14);

  /* Typography */
  --font-sans: "Plus Jakarta Sans", "Inter", system-ui, -apple-system,
               "Segoe UI", Roboto, Helvetica, Arial, sans-serif;

  /* Layout */
  --maxw: 1180px;
  --radius: 14px;
  --radius-lg: 22px;
  --gutter: clamp(20px, 5vw, 40px);
  --nav-h: 76px;

  /* Motion */
  --ease: cubic-bezier(.22, 1, .36, 1);
  --t-fast: .18s;
  --t: .32s;
}

/* --------------------------------------------------------------------------
   SECTION: Reset & base
   -------------------------------------------------------------------------- */
*, *::before, *::after { box-sizing: border-box; }
html { scroll-behavior: smooth; -webkit-text-size-adjust: 100%; }
@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  * { animation-duration: .001ms !important; transition-duration: .001ms !important; }
}
body {
  margin: 0;
  font-family: var(--font-sans);
  color: var(--ink);
  background-color: var(--page);
  background-image:
    radial-gradient(1100px 560px at 100% -8%, rgba(184,115,51,.06), transparent 58%),
    radial-gradient(900px 520px at -10% 6%, rgba(15,42,63,.05), transparent 55%);
  background-attachment: fixed;
  background-repeat: no-repeat;
  line-height: 1.65;
  font-size: 17px;
  -webkit-font-smoothing: antialiased;
  text-rendering: optimizeLegibility;
  overflow-x: hidden;
}
img, svg, video { max-width: 100%; display: block; }
a { color: var(--orange-dark); text-decoration: none; transition: color var(--t-fast) var(--ease); }
a:hover { color: var(--orange); }
ul { margin: 0; padding: 0; list-style: none; }

h1, h2, h3, h4 { color: var(--navy); line-height: 1.15; margin: 0 0 .5em; font-weight: 700; letter-spacing: -.02em; }
h1 { font-size: clamp(2.1rem, 5vw, 3.4rem); font-weight: 800; }
h2 { font-size: clamp(1.7rem, 3.4vw, 2.5rem); }
h3 { font-size: clamp(1.2rem, 2vw, 1.5rem); }
p  { margin: 0 0 1rem; color: var(--slate); }
:focus-visible { outline: 3px solid var(--orange); outline-offset: 3px; border-radius: 6px; }

/* --------------------------------------------------------------------------
   SECTION: Layout helpers
   -------------------------------------------------------------------------- */
.container { width: 100%; max-width: var(--maxw); margin-inline: auto; padding-inline: var(--gutter); }
.section { padding-block: clamp(64px, 9vw, 120px); }
.section--tight { padding-block: clamp(48px, 6vw, 80px); }
.section--mist { background: var(--mist); }
.section--navy { background: var(--navy-deep); color: #D8E2EA; }
.section--navy h2, .section--navy h3 { color: #fff; }
.center { text-align: center; }
.measure { max-width: 720px; margin-inline: auto; }
.grid { display: grid; gap: clamp(20px, 3vw, 32px); }
@media (min-width: 720px)  { .grid--2 { grid-template-columns: repeat(2, 1fr); } }
@media (min-width: 880px)  { .grid--3 { grid-template-columns: repeat(3, 1fr); } }
@media (min-width: 980px)  { .grid--4 { grid-template-columns: repeat(4, 1fr); } }

.eyebrow {
  display: inline-flex; align-items: center; gap: .5rem;
  font-size: .8rem; font-weight: 700; letter-spacing: .14em; text-transform: uppercase;
  color: var(--orange-dark); margin-bottom: 1rem;
}
.eyebrow::before { content: ""; width: 26px; height: 2px; background: var(--orange); border-radius: 2px; }
.section--navy .eyebrow { color: #F7A579; }

.lead { font-size: 1.18rem; color: var(--slate); }

/* --------------------------------------------------------------------------
   SECTION: Buttons / CTAs
   -------------------------------------------------------------------------- */
.btn {
  --btn-bg: var(--orange); --btn-fg: #fff;
  display: inline-flex; align-items: center; justify-content: center; gap: .55rem;
  padding: .9rem 1.6rem; border-radius: 999px; font-weight: 700; font-size: 1rem;
  background: var(--btn-bg); color: var(--btn-fg); border: 2px solid transparent;
  cursor: pointer; transition: transform var(--t-fast) var(--ease),
              box-shadow var(--t) var(--ease), background var(--t-fast) var(--ease);
  box-shadow: 0 8px 20px rgba(242, 101, 34, .28); will-change: transform;
}
.btn:hover { color: #fff; background: var(--orange-dark); transform: translateY(-2px); box-shadow: 0 14px 30px rgba(242, 101, 34, .38); }
.btn:active { transform: translateY(0); }
.btn--ghost { background: transparent; color: var(--navy); border-color: var(--line); box-shadow: none; }
.btn--ghost:hover { background: var(--navy); color: #fff; border-color: var(--navy); transform: translateY(-2px); box-shadow: var(--shadow-md); }
.btn--light { background: #fff; color: var(--navy); box-shadow: var(--shadow-md); }
.btn--light:hover { background: #fff; color: var(--orange-dark); }
.btn--lg { padding: 1.05rem 2rem; font-size: 1.05rem; }
.btn .ico { width: 18px; height: 18px; transition: transform var(--t) var(--ease); }
.btn:hover .ico { transform: translateX(3px); }

/* --------------------------------------------------------------------------
   SECTION: Header / Navigation (with dropdowns)
   -------------------------------------------------------------------------- */
.site-header {
  position: sticky; top: 0; z-index: 1000;
  background: rgba(255,255,255,.82); backdrop-filter: saturate(180%) blur(14px);
  border-bottom: 1px solid transparent;
  transition: box-shadow var(--t) var(--ease), border-color var(--t) var(--ease), background var(--t) var(--ease);
}
.site-header.is-scrolled { box-shadow: var(--shadow-sm); border-color: var(--line); }

/* Theranostic Principle banner — sits directly below the nav */
.principle-banner { background: linear-gradient(120deg, var(--copper-deep), var(--copper) 45%, var(--orange) 100%); color: #fff; }
.principle-banner__inner { display: flex; align-items: center; justify-content: center; flex-wrap: wrap; gap: .5rem 1.2rem; padding-block: 1.6rem; text-align: center; }
.principle-banner__label { font-size: .82rem; font-weight: 800; letter-spacing: .16em; text-transform: uppercase; color: #FCE4CF; }
.principle-banner__label::after { content: "·"; margin-left: 1.2rem; color: rgba(255,255,255,.6); }
.principle-banner__tagline { font-size: 1.12rem; font-weight: 800; color: #fff; letter-spacing: -.01em; text-shadow: 0 1px 6px rgba(0,0,0,.18); }
@media (max-width: 560px) { .principle-banner__label::after { display: none; } }
.nav { display: flex; align-items: center; justify-content: space-between; height: var(--nav-h); gap: 1rem; }
.brand { display: inline-flex; align-items: center; gap: .6rem; font-weight: 800; color: var(--navy); font-size: 1.18rem; letter-spacing: -.02em; }
.brand:hover { color: var(--navy); }
.brand__logo { height: 42px; width: auto; flex: 0 0 auto; }
.site-footer .brand__logo { height: 46px; filter: brightness(0) invert(1); opacity: .95; }

.nav__links { display: none; align-items: center; gap: .2rem; }
@media (min-width: 1040px) { .nav__links { display: flex; } }
.nav__item { position: relative; }
.nav__link {
  display: inline-flex; align-items: center; gap: .3rem;
  padding: .6rem .85rem; border-radius: 10px; font-weight: 600; color: var(--navy);
  transition: background var(--t-fast) var(--ease), color var(--t-fast) var(--ease);
}
.nav__link:hover, .nav__item:hover > .nav__link, .nav__link[aria-current="page"] { color: var(--orange-dark); background: var(--orange-soft); }
.nav__link .caret { width: 12px; height: 12px; transition: transform var(--t) var(--ease); }
.nav__item:hover .caret { transform: rotate(180deg); }

/* Dropdown */
.dropdown {
  position: absolute; top: calc(100% + 8px); left: 0; min-width: 240px;
  background: #fff; border: 1px solid var(--line); border-radius: var(--radius);
  box-shadow: var(--shadow-lg); padding: .5rem; opacity: 0; visibility: hidden;
  transform: translateY(8px); transition: opacity var(--t) var(--ease),
              transform var(--t) var(--ease), visibility var(--t);
}
.nav__item:hover .dropdown, .nav__item:focus-within .dropdown { opacity: 1; visibility: visible; transform: translateY(0); }
.dropdown a {
  display: flex; flex-direction: column; gap: 1px; padding: .6rem .75rem; border-radius: 10px; color: var(--navy);
}
.dropdown a:hover { background: var(--mist); color: var(--orange-dark); }
.dropdown a span { font-weight: 700; }
.dropdown a small { color: var(--slate); font-weight: 500; }

.nav__cta { display: none; }
@media (min-width: 1040px) { .nav__cta { display: inline-flex; } }

/* Mobile nav toggle */
.nav__toggle {
  display: inline-flex; flex-direction: column; gap: 5px; justify-content: center;
  width: 48px; height: 48px; padding: 0 12px; background: #fff; border: 1px solid var(--line);
  border-radius: 12px; cursor: pointer; box-shadow: var(--shadow-sm);
  transition: border-color var(--t-fast) var(--ease), box-shadow var(--t-fast) var(--ease);
}
.nav__toggle:hover { border-color: var(--orange); }
@media (min-width: 1040px) { .nav__toggle { display: none; } }
.nav__toggle span { height: 2.5px; background: var(--navy); border-radius: 2px; transition: transform var(--t) var(--ease), opacity var(--t) var(--ease); }
.nav__toggle[aria-expanded="true"] span:nth-child(1) { transform: translateY(7px) rotate(45deg); }
.nav__toggle[aria-expanded="true"] span:nth-child(2) { opacity: 0; }
.nav__toggle[aria-expanded="true"] span:nth-child(3) { transform: translateY(-7px) rotate(-45deg); }

/* Mobile drawer */
.mobile-nav {
  position: fixed; top: var(--nav-h); right: 0; bottom: 0; left: 0; z-index: 999; background: #fff;
  padding: 1.25rem var(--gutter) 2rem; overflow-y: auto;
  transform: translateX(100%); transition: transform var(--t) var(--ease); visibility: hidden;
}
.mobile-nav.is-open { transform: translateX(0); visibility: visible; }
.mobile-nav a { display: block; padding: .9rem .25rem; font-size: 1.15rem; font-weight: 700; color: var(--navy); border-bottom: 1px solid var(--line); }
.mobile-nav .sub a { font-size: 1rem; font-weight: 600; color: var(--slate); padding-left: 1rem; }
.mobile-nav .btn { width: 100%; margin-top: 1.25rem; }

/* --------------------------------------------------------------------------
   SECTION: Hero
   -------------------------------------------------------------------------- */
.hero { position: relative; overflow: hidden; background: linear-gradient(180deg, #FFFFFF 0%, var(--page) 100%); color: var(--ink); isolation: isolate; border-bottom: 1px solid var(--line); }
.hero::before, .hero::after { content: ""; position: absolute; border-radius: 50%; filter: blur(70px); z-index: -1; }
.hero::before { width: 540px; height: 540px; background: radial-gradient(circle, rgba(242,101,34,.16), transparent 70%); top: -180px; right: -150px; animation: float 16s var(--ease) infinite alternate; }
.hero::after  { width: 460px; height: 460px; background: radial-gradient(circle, rgba(15,42,63,.08), transparent 70%); bottom: -180px; left: -150px; animation: float 20s var(--ease) infinite alternate-reverse; }
@keyframes float { to { transform: translate3d(40px, 30px, 0) scale(1.08); } }
@keyframes pulse { 0%,100% { opacity: .35; } 50% { opacity: 1; } }
@keyframes spin  { to { transform: rotate(360deg); } }

.hero__inner { display: grid; gap: clamp(32px, 5vw, 56px); align-items: center; padding-block: clamp(52px, 8vw, 96px); }
@media (min-width: 940px) { .hero__inner { grid-template-columns: 1.08fr .92fr; } }
.hero h1 { color: var(--navy); }
.hero h1 .accent { color: var(--orange-dark); }
.hero p { color: var(--slate); font-size: 1.16rem; max-width: 52ch; }
.hero .eyebrow { color: var(--orange-dark); }
.hero__cta { display: flex; flex-wrap: wrap; gap: .9rem; margin-top: 1.8rem; }
.hero__badges { display: flex; flex-wrap: wrap; gap: 1.2rem 1.8rem; margin-top: 2.2rem; padding-top: 1.5rem; border-top: 1px solid var(--line); }
.hero__badge { font-size: .88rem; color: var(--slate); }
.hero__badge strong { display: block; color: var(--navy); font-size: 1.35rem; font-weight: 800; }

/* Investigational pill */
.hero__pill { display: inline-flex; align-items: center; gap: .5rem; padding: .4rem .9rem; border-radius: 999px;
  background: #fff; border: 1px solid var(--line); box-shadow: var(--shadow-sm); margin-bottom: 1.1rem;
  font-size: .74rem; font-weight: 800; letter-spacing: .1em; text-transform: uppercase; color: var(--copper-deep); }
.hero__pill::before { content: ""; width: 8px; height: 8px; border-radius: 50%; background: var(--copper); box-shadow: 0 0 0 4px rgba(184,115,51,.18); animation: pulse 2.4s var(--ease) infinite; }

/* Hero right column: dark video card (accent) + stat + note */
.hero__visual { display: grid; gap: 1rem; }
.hero-video { position: relative; display: block; border-radius: var(--radius-lg); overflow: hidden; aspect-ratio: 16/10; color: #fff;
  background: radial-gradient(circle at 50% 38%, rgba(242,101,34,.4), transparent 60%), var(--navy-deep);
  box-shadow: var(--shadow-lg); border: 1px solid rgba(255,255,255,.08); transition: transform var(--t) var(--ease), box-shadow var(--t) var(--ease); }
.hero-video:hover { transform: translateY(-3px); box-shadow: 0 36px 70px rgba(15,42,63,.22); color: #fff; }
.hero-video .label { position: absolute; top: 1.1rem; left: 1.2rem; font-size: .72rem; font-weight: 800; letter-spacing: .14em; text-transform: uppercase; color: #F7A579; }
.hero-video__inner { position: absolute; inset: 0; display: grid; place-items: center; text-align: center; padding: 1.4rem; }
.hero-video .play { width: 70px; height: 70px; border-radius: 50%; background: var(--orange); display: grid; place-items: center; margin: 0 auto .9rem; box-shadow: 0 12px 28px rgba(242,101,34,.5); transition: transform var(--t) var(--ease); }
.hero-video:hover .play { transform: scale(1.08); }
.hero-video .play svg { width: 26px; height: 26px; color: #fff; margin-left: 4px; }
.hero-video strong { display: block; color: #fff; font-size: 1.1rem; }
.hero-video small { color: #9FB4C2; }
.hero-aside { display: grid; gap: 1rem; grid-template-columns: minmax(120px,auto) 1fr; align-items: stretch; }
@media (max-width: 560px) { .hero-aside { grid-template-columns: 1fr; } }
.hero-stat { text-align: center; display: grid; place-content: center; background: #fff; border: 1px solid var(--line); border-radius: 14px; padding: 1rem 1.1rem; box-shadow: var(--shadow-sm); }
.hero-stat strong { display: block; font-size: 1.7rem; font-weight: 800; color: var(--orange); letter-spacing: -.02em; }
.hero-stat span { font-size: .74rem; color: var(--slate); }
.hero-note { background: var(--orange-soft); border: 1px solid #F2C9A3; border-radius: 14px; padding: .9rem 1.1rem; font-size: .9rem; color: var(--ink); display: flex; align-items: center; }
.hero-note strong { color: var(--copper-deep); }

/* Hero title block (company name large, then the positioning subhead) */
.hero__title { font-size: clamp(2.9rem, 6.4vw, 4.6rem); font-weight: 800; letter-spacing: -.035em; line-height: 1.02; margin-bottom: .6rem; }
.hero__subhead { font-size: clamp(1.3rem, 2.6vw, 1.9rem); font-weight: 700; color: var(--navy); max-width: 24ch; line-height: 1.18; }
.hero__subhead .accent { color: var(--orange-dark); }
.hero__tnbc { font-size: 1.04rem; color: var(--slate); font-weight: 500; margin-top: 1rem; }

/* Lead Clinical Opportunity card (replaces the hero video) */
.lead-card { background: #fff; border: 1px solid var(--line); border-radius: var(--radius-lg); padding: clamp(1.5rem, 3vw, 2rem); box-shadow: var(--shadow-md); display: grid; gap: 1rem; }
.lead-card .tag-pill { justify-self: start; }
.lead-card__title { font-size: clamp(1.4rem, 2.4vw, 1.85rem); color: var(--navy); line-height: 1.2; }
.lead-card__title strong { color: var(--orange-dark); }
.lead-card p { font-size: 1rem; color: var(--slate); max-width: none; }
.lead-card__stat { display: grid; grid-template-columns: auto 1fr; gap: .2rem 1rem; align-items: center; background: var(--orange-soft); border: 1px solid #F2C9A3; border-radius: 14px; padding: 1rem 1.1rem; margin-top: .3rem; }
.lead-card__stat strong { font-size: clamp(1.9rem, 4vw, 2.3rem); font-weight: 800; color: var(--orange); letter-spacing: -.02em; line-height: 1; }
.lead-card__stat span { font-size: .82rem; color: var(--ink); }

/* Copper accent band — paired-isotope facts */
.copper-facts { display: grid; gap: 1.6rem 2.6rem; grid-template-columns: 1fr; }
@media (min-width: 760px) { .copper-facts { grid-template-columns: minmax(0, .9fr) minmax(0, 2.1fr); align-items: center; } }
.copper-fact { display: grid; grid-template-columns: auto 1fr; gap: 1rem; align-items: center; color: #fff; }
.copper-fact > strong { font-size: clamp(2.4rem, 5vw, 3.2rem); font-weight: 800; line-height: 1; letter-spacing: -.03em; }
.copper-fact span { color: rgba(255,255,255,.92); font-size: .95rem; line-height: 1.5; }
.copper-fact b { color: #fff; font-weight: 800; }

/* --------------------------------------------------------------------------
   SECTION: Logo / trust strip
   -------------------------------------------------------------------------- */
.trust { background: var(--navy); color: #CddBe5; }
.trust .container { display: flex; flex-wrap: wrap; align-items: center; justify-content: center; gap: 1rem 2.4rem; padding-block: 1.1rem; }
.trust span { font-size: .82rem; letter-spacing: .12em; text-transform: uppercase; color: #9FB4C2; font-weight: 600; }

/* --------------------------------------------------------------------------
   SECTION: Cards
   -------------------------------------------------------------------------- */
.card {
  background: #fff; border: 1px solid var(--line); border-radius: var(--radius-lg);
  padding: 2rem 1.7rem; box-shadow: var(--shadow-sm);
  transition: transform var(--t) var(--ease), box-shadow var(--t) var(--ease), border-color var(--t) var(--ease);
  height: 100%;
}
.card:hover { transform: translateY(-6px); box-shadow: var(--shadow-lg); border-color: #F2C4A8; }
.card__icon {
  width: 56px; height: 56px; display: grid; place-items: center; border-radius: 16px;
  background: var(--orange-soft); color: var(--orange-dark); margin-bottom: 1.2rem;
  transition: transform var(--t) var(--ease), background var(--t) var(--ease);
}
.card:hover .card__icon { transform: scale(1.06) rotate(-4deg); }
.card__icon svg { width: 28px; height: 28px; }
.card h3 { margin-bottom: .4rem; }
.card p { margin-bottom: 0; font-size: .98rem; }
.card__link { display: inline-flex; align-items: center; gap: .35rem; margin-top: 1rem; font-weight: 700; }
.card__link .ico { width: 16px; height: 16px; transition: transform var(--t) var(--ease); }
.card__link:hover .ico { transform: translateX(4px); }

/* --------------------------------------------------------------------------
   SECTION: Stats band
   -------------------------------------------------------------------------- */
.stats { display: grid; gap: 1.5rem; grid-template-columns: repeat(2, 1fr); }
@media (min-width: 820px) { .stats { grid-template-columns: repeat(4, 1fr); } }
.stat { text-align: center; padding: 1.2rem; }
.stat strong { display: block; font-size: clamp(2rem, 5vw, 2.9rem); font-weight: 800; color: var(--orange); letter-spacing: -.03em; }
.stat span { font-size: .96rem; color: var(--slate); }
.section--navy .stat span { color: #AFC0CC; }

/* --------------------------------------------------------------------------
   SECTION: Split feature (image/text)
   -------------------------------------------------------------------------- */
.split { display: grid; gap: clamp(32px, 5vw, 60px); align-items: center; }
@media (min-width: 900px) { .split { grid-template-columns: 1fr 1fr; } .split--rev .split__media { order: 2; } }
.split__media {
  border-radius: var(--radius-lg); overflow: hidden; box-shadow: var(--shadow-md);
  background: linear-gradient(160deg, var(--orange-soft), #fff); aspect-ratio: 4/3; position: relative;
  display: grid; place-items: center; border: 1px solid var(--line);
}
.split__media svg { width: 70%; height: auto; }
.checklist li { display: flex; gap: .7rem; align-items: flex-start; margin-bottom: .7rem; color: var(--ink); }
.checklist svg { width: 22px; height: 22px; flex: 0 0 auto; color: var(--ok); margin-top: 2px; }

/* --------------------------------------------------------------------------
   SECTION: Pipeline / indications
   -------------------------------------------------------------------------- */
.indications { display: grid; gap: .9rem; grid-template-columns: 1fr; }
@media (min-width: 640px) { .indications { grid-template-columns: 1fr 1fr; } }
@media (min-width: 980px) { .indications { grid-template-columns: 1fr 1fr 1fr; } }
.indication { background: #fff; border: 1px solid var(--line); border-radius: 12px; padding: .85rem 1rem; }
.indication__head { display: flex; justify-content: space-between; align-items: baseline; gap: 1rem; margin-bottom: .4rem; }
.indication__name { font-weight: 700; color: var(--navy); font-size: .98rem; }
.indication__pct { font-weight: 800; color: var(--orange); font-size: .98rem; }
.bar { height: 7px; background: var(--orange-soft); border-radius: 999px; overflow: hidden; }
.bar > i { display: block; height: 100%; background: linear-gradient(90deg, var(--orange), var(--orange-dark)); border-radius: 999px; width: 0; transition: width 1.2s var(--ease); }

/* --------------------------------------------------------------------------
   SECTION: Video block (VP Pack)
   -------------------------------------------------------------------------- */
.video-wrap { position: relative; border-radius: var(--radius-lg); overflow: hidden; box-shadow: var(--shadow-lg); background: var(--navy-deep); aspect-ratio: 16/9; border: 1px solid rgba(255,255,255,.1); }
.video-wrap iframe, .video-wrap video { position: absolute; inset: 0; width: 100%; height: 100%; border: 0; }
.video-placeholder { position: absolute; inset: 0; display: grid; place-items: center; text-align: center; color: #fff;
  background: radial-gradient(circle at 50% 40%, rgba(242,101,34,.35), transparent 60%), var(--navy-deep); cursor: pointer; }
.video-placeholder .play { width: 84px; height: 84px; border-radius: 50%; background: var(--orange); display: grid; place-items: center; margin: 0 auto 1rem; box-shadow: 0 12px 30px rgba(242,101,34,.5); transition: transform var(--t) var(--ease); }
.video-placeholder:hover .play { transform: scale(1.08); }
.video-placeholder .play svg { width: 32px; height: 32px; color: #fff; margin-left: 4px; }
.video-placeholder small { display: block; color: #9FB4C2; margin-top: .4rem; }

/* --------------------------------------------------------------------------
   SECTION: Team
   -------------------------------------------------------------------------- */
.team-grid { display: grid; gap: 1.4rem; grid-template-columns: repeat(2, 1fr); }
@media (min-width: 760px) { .team-grid { grid-template-columns: repeat(3, 1fr); } }
.member { text-align: center; background: #fff; border: 1px solid var(--line); border-radius: var(--radius-lg); padding: 1.8rem 1.2rem; transition: transform var(--t) var(--ease), box-shadow var(--t) var(--ease); }
.member:hover { transform: translateY(-5px); box-shadow: var(--shadow-md); }
.member__avatar { width: 104px; height: 104px; border-radius: 50%; margin: 0 auto 1rem; display: grid; place-items: center; font-weight: 800; font-size: 1.6rem; color: #fff; background: linear-gradient(150deg, var(--orange), var(--navy)); overflow: hidden; position: relative; box-shadow: 0 6px 18px rgba(15,42,63,.18); }
.member__avatar img { width: 100%; height: 100%; object-fit: cover; filter: grayscale(100%) contrast(1.02); transition: filter var(--t) var(--ease), transform var(--t) var(--ease); }
.member:hover .member__avatar img { filter: grayscale(0%); transform: scale(1.05); }
.member__avatar::after { content: ""; position: absolute; inset: 0; border-radius: 50%; box-shadow: inset 0 0 0 2px rgba(242,101,34,.0); transition: box-shadow var(--t) var(--ease); }
.member:hover .member__avatar::after { box-shadow: inset 0 0 0 3px var(--orange); }
.member h3 { font-size: 1.1rem; margin-bottom: .15rem; }
.member span { color: var(--orange-dark); font-weight: 600; font-size: .92rem; }

/* --------------------------------------------------------------------------
   SECTION: News cards
   -------------------------------------------------------------------------- */
.news { display: grid; gap: 1.6rem; grid-template-columns: 1fr; }
@media (min-width: 760px) { .news { grid-template-columns: repeat(3, 1fr); } }
.post { display: flex; flex-direction: column; background: #fff; border: 1px solid var(--line); border-radius: var(--radius-lg); overflow: hidden; transition: transform var(--t) var(--ease), box-shadow var(--t) var(--ease); }
.post:hover { transform: translateY(-5px); box-shadow: var(--shadow-md); }
.post__img { aspect-ratio: 16/9; background: linear-gradient(150deg, var(--navy), var(--navy-700)); display: grid; place-items: center; }
.post__img svg { width: 60px; height: 60px; color: rgba(255,255,255,.5); }
.post__body { padding: 1.4rem; display: flex; flex-direction: column; flex: 1; }
.post__tag { font-size: .74rem; font-weight: 700; letter-spacing: .1em; text-transform: uppercase; color: var(--orange-dark); }
.post__date { font-size: .85rem; color: var(--slate); }
.post h3 { font-size: 1.12rem; margin: .5rem 0 .8rem; }
.post .card__link { margin-top: auto; }

/* --------------------------------------------------------------------------
   SECTION: Contact / Forms
   -------------------------------------------------------------------------- */
.contact-grid { display: grid; gap: clamp(28px, 4vw, 48px); }
@media (min-width: 920px) { .contact-grid { grid-template-columns: 1fr 1.1fr; } }
.contact-info { background: var(--navy-deep); color: #C9D6DF; border-radius: var(--radius-lg); padding: clamp(1.8rem, 4vw, 2.6rem); }
.contact-info h3 { color: #fff; }
.contact-info .row { display: flex; gap: .9rem; align-items: flex-start; margin-bottom: 1.3rem; }
.contact-info .row svg { width: 22px; height: 22px; color: var(--orange); flex: 0 0 auto; margin-top: 3px; }
.contact-info a { color: #fff; }
.contact-info .row strong { display: block; color: #fff; }

.form-card { background: #fff; border: 1px solid var(--line); border-radius: var(--radius-lg); padding: clamp(1.6rem, 4vw, 2.4rem); box-shadow: var(--shadow-sm); }
.field { margin-bottom: 1.1rem; }
.field label { display: block; font-weight: 600; font-size: .9rem; color: var(--navy); margin-bottom: .4rem; }
.field label .req { color: var(--orange); }
.field input, .field select, .field textarea {
  width: 100%; padding: .8rem .95rem; font: inherit; font-size: .98rem; color: var(--ink);
  background: var(--mist); border: 1.5px solid var(--line); border-radius: 12px;
  transition: border-color var(--t-fast) var(--ease), background var(--t-fast) var(--ease), box-shadow var(--t-fast) var(--ease);
}
.field input:focus, .field select:focus, .field textarea:focus { outline: none; border-color: var(--orange); background: #fff; box-shadow: 0 0 0 4px rgba(242,101,34,.12); }
.field textarea { resize: vertical; min-height: 120px; }
.field--row { display: grid; gap: 1.1rem; }
@media (min-width: 560px) { .field--row { grid-template-columns: 1fr 1fr; } }
.form-note { font-size: .82rem; color: var(--slate); margin-top: .4rem; }
.form-status { margin-top: 1rem; padding: .9rem 1.1rem; border-radius: 12px; font-weight: 600; display: none; }
.form-status.ok  { display: block; background: #E6F6EE; color: #1d7a4d; border: 1px solid #BCE8D0; }
.form-status.err { display: block; background: #FCEBE7; color: #b23a1a; border: 1px solid #F6C9BB; }

/* --------------------------------------------------------------------------
   SECTION: CTA band
   -------------------------------------------------------------------------- */
.cta-band { background: linear-gradient(135deg, var(--orange), var(--orange-dark)); color: #fff; border-radius: var(--radius-lg); padding: clamp(2.4rem, 5vw, 3.6rem); text-align: center; position: relative; overflow: hidden; }
.cta-band h2 { color: #fff; }
.cta-band p { color: rgba(255,255,255,.92); }
.cta-band .btn { margin-top: 1.4rem; }

/* --------------------------------------------------------------------------
   SECTION: Page hero (interior pages)
   -------------------------------------------------------------------------- */
.page-hero { background: linear-gradient(180deg, #FFFFFF 0%, var(--page) 100%); color: var(--ink); padding-block: clamp(48px, 7vw, 84px); position: relative; overflow: hidden; border-bottom: 1px solid var(--line); }
.page-hero::after { content: ""; position: absolute; width: 440px; height: 440px; border-radius: 50%; background: radial-gradient(circle, rgba(242,101,34,.14), transparent 70%); top: -180px; right: -140px; filter: blur(60px); }
.page-hero h1 { color: var(--navy); position: relative; }
.page-hero p { color: var(--slate); max-width: 62ch; position: relative; }
.breadcrumbs { font-size: .85rem; color: var(--slate); margin-bottom: .8rem; position: relative; }
.breadcrumbs a { color: var(--orange-dark); }
/* lead-indication pill on the now-light page hero */
.page-hero .tag-pill { background: var(--orange-soft); border-color: #F2C9A3; color: var(--orange-dark); }
.page-hero .tag-pill::before { background: var(--orange); }

/* --------------------------------------------------------------------------
   SECTION: Footer
   -------------------------------------------------------------------------- */
.site-footer { background: var(--navy-deep); color: #9FB4C2; padding-block: clamp(48px, 6vw, 72px) 0; }
.footer-grid { display: grid; gap: 2.2rem; grid-template-columns: 1fr; }
@media (min-width: 720px) { .footer-grid { grid-template-columns: 1.4fr 1fr 1fr; } }
.site-footer h4 { color: #fff; font-size: .95rem; letter-spacing: .04em; margin-bottom: 1.1rem; }
.site-footer a { color: #B7C6D2; }
.site-footer a:hover { color: var(--orange); }
.site-footer .brand { color: #fff; }
.site-footer .brand small { color: #8AA0AE; }
.footer-links li { margin-bottom: .6rem; }
.footer-contact .row { display: flex; gap: .6rem; margin-bottom: .7rem; font-size: .94rem; }
.footer-contact svg { width: 18px; height: 18px; color: var(--orange); flex: 0 0 auto; margin-top: 3px; }
.footer-bottom { border-top: 1px solid rgba(255,255,255,.1); margin-top: 2.6rem; padding-block: 1.5rem; display: flex; flex-wrap: wrap; gap: .6rem 1.4rem; justify-content: space-between; font-size: .85rem; }
.footer-disclaimer { font-size: .78rem; color: #708796; max-width: 70ch; margin-top: .6rem; }

/* --------------------------------------------------------------------------
   SECTION: AI Chat widget
   -------------------------------------------------------------------------- */
.chat-fab {
  position: fixed; right: 22px; bottom: 22px; z-index: 1100;
  width: 62px; height: 62px; border-radius: 50%; border: none; cursor: pointer;
  background: var(--orange); color: #fff; box-shadow: 0 12px 30px rgba(242,101,34,.45);
  display: grid; place-items: center; transition: transform var(--t) var(--ease), background var(--t) var(--ease);
}
.chat-fab:hover { transform: scale(1.06); background: var(--orange-dark); }
.chat-fab svg { width: 28px; height: 28px; }
.chat-fab .close-ico { display: none; }
.chat-fab.is-open .open-ico { display: none; }
.chat-fab.is-open .close-ico { display: block; }

.chat-panel {
  position: fixed; right: 22px; bottom: 96px; z-index: 1100;
  width: min(380px, calc(100vw - 32px)); height: min(560px, calc(100vh - 130px));
  background: #fff; border-radius: 20px; box-shadow: var(--shadow-lg); border: 1px solid var(--line);
  display: flex; flex-direction: column; overflow: hidden;
  opacity: 0; visibility: hidden; transform: translateY(16px) scale(.98);
  transition: opacity var(--t) var(--ease), transform var(--t) var(--ease), visibility var(--t);
}
.chat-panel.is-open { opacity: 1; visibility: visible; transform: translateY(0) scale(1); }
.chat-head { background: var(--navy-deep); color: #fff; padding: 1.1rem 1.2rem; display: flex; gap: .8rem; align-items: center; }
.chat-head .avatar { width: 40px; height: 40px; border-radius: 50%; background: var(--orange); display: grid; place-items: center; flex: 0 0 auto; }
.chat-head .avatar svg { width: 22px; height: 22px; color: #fff; }
.chat-head strong { display: block; font-size: 1rem; }
.chat-head small { color: #9FB4C2; font-size: .8rem; }
.chat-head .status-dot { width: 8px; height: 8px; border-radius: 50%; background: #4ade80; display: inline-block; margin-right: 5px; }

.chat-body { flex: 1; overflow-y: auto; padding: 1.1rem; background: var(--mist); display: flex; flex-direction: column; gap: .8rem; }
.msg { max-width: 84%; padding: .7rem .95rem; border-radius: 16px; font-size: .94rem; line-height: 1.5; }
.msg.bot { background: #fff; border: 1px solid var(--line); border-bottom-left-radius: 5px; align-self: flex-start; color: var(--ink); }
.msg.user { background: var(--orange); color: #fff; border-bottom-right-radius: 5px; align-self: flex-end; }
.msg.bot a { font-weight: 700; }
.chat-suggestions { display: flex; flex-wrap: wrap; gap: .5rem; padding: 0 1.1rem .8rem; background: var(--mist); }
.chip { font-size: .82rem; padding: .45rem .8rem; border-radius: 999px; background: #fff; border: 1px solid var(--line); color: var(--navy); cursor: pointer; transition: all var(--t-fast) var(--ease); }
.chip:hover { background: var(--orange-soft); border-color: var(--orange); color: var(--orange-dark); }
.chat-foot { display: flex; gap: .5rem; padding: .8rem; border-top: 1px solid var(--line); background: #fff; }
.chat-foot input { flex: 1; padding: .7rem .9rem; border: 1.5px solid var(--line); border-radius: 999px; font: inherit; font-size: .92rem; }
.chat-foot input:focus { outline: none; border-color: var(--orange); }
.chat-foot button { width: 44px; height: 44px; border-radius: 50%; border: none; background: var(--orange); color: #fff; cursor: pointer; display: grid; place-items: center; flex: 0 0 auto; transition: background var(--t-fast) var(--ease); }
.chat-foot button:hover { background: var(--orange-dark); }
.chat-foot button svg { width: 20px; height: 20px; }
.typing { display: inline-flex; gap: 4px; }
.typing i { width: 7px; height: 7px; border-radius: 50%; background: var(--slate); animation: blink 1.2s infinite both; }
.typing i:nth-child(2) { animation-delay: .2s; } .typing i:nth-child(3) { animation-delay: .4s; }
@keyframes blink { 0%, 60%, 100% { opacity: .25; } 30% { opacity: 1; } }

/* --------------------------------------------------------------------------
   SECTION: Scroll reveal animations
   -------------------------------------------------------------------------- */
[data-reveal] { opacity: 0; transform: translateY(26px); transition: opacity .7s var(--ease), transform .7s var(--ease); }
[data-reveal].is-visible { opacity: 1; transform: none; }
[data-reveal][data-delay="1"] { transition-delay: .08s; }
[data-reveal][data-delay="2"] { transition-delay: .16s; }
[data-reveal][data-delay="3"] { transition-delay: .24s; }
[data-reveal][data-delay="4"] { transition-delay: .32s; }

/* --------------------------------------------------------------------------
   SECTION: Utilities
   -------------------------------------------------------------------------- */
/* --------------------------------------------------------------------------
   SECTION: Mobile refinements (small-screen safety)
   -------------------------------------------------------------------------- */
@media (max-width: 600px) {
  /* Tab toggle: go full-width so the two pills never overflow the screen */
  .tabs__nav { display: flex; width: 100%; }
  .tabs__btn { flex: 1 1 0; min-width: 0; padding: .7rem .55rem; font-size: .9rem; text-align: center; }
  /* Keep big stat numbers from crowding in 2-up grids */
  .stat strong { font-size: 1.95rem; }
  .fact strong { font-size: 1.35rem; }
  /* Tighten section rhythm a touch on phones */
  .section { padding-block: clamp(48px, 12vw, 72px); }
}
@media (max-width: 380px) {
  /* Single-column stats on the narrowest phones to avoid cramped numbers */
  .stats { grid-template-columns: 1fr; }
}

.mt-0 { margin-top: 0; } .mb-0 { margin-bottom: 0; }
.skip-link { position: absolute; left: -9999px; top: 0; background: var(--navy); color: #fff; padding: .8rem 1.2rem; border-radius: 0 0 10px 0; z-index: 2000; }
.skip-link:focus { left: 0; color: #fff; }
.visually-hidden { position: absolute; width: 1px; height: 1px; overflow: hidden; clip: rect(0 0 0 0); }

/* --------------------------------------------------------------------------
   SECTION: Lead program (breast cancer / TNBC spotlight)
   -------------------------------------------------------------------------- */
.lead-program { position: relative; background:
   linear-gradient(135deg, rgba(15,42,63,.96), rgba(10,30,45,.96)); color: #fff;
   border-radius: var(--radius-lg); overflow: hidden; }
.lead-program::before { content: ""; position: absolute; inset: 0;
   background: radial-gradient(circle at 85% 15%, rgba(242,101,34,.30), transparent 55%); }
.lead-program__inner { position: relative; display: grid; gap: clamp(28px,4vw,52px); align-items: center; padding: clamp(2rem,5vw,3.4rem); }
@media (min-width: 920px) { .lead-program__inner { grid-template-columns: 1.1fr .9fr; } }
.lead-program h2, .lead-program h3 { color: #fff; }
.lead-program p { color: #C9D6DF; }
.tag-pill { display: inline-flex; align-items: center; gap: .5rem; padding: .4rem .9rem; border-radius: 999px;
   background: rgba(242,101,34,.16); border: 1px solid rgba(242,101,34,.4); color: #F7A579;
   font-size: .8rem; font-weight: 700; letter-spacing: .08em; text-transform: uppercase; margin-bottom: 1rem; }
.tag-pill::before { content: ""; width: 8px; height: 8px; border-radius: 50%; background: var(--orange); box-shadow: 0 0 0 4px rgba(242,101,34,.25); animation: pulse 2.4s var(--ease) infinite; }
.lead-program__facts { display: grid; gap: 1rem; }
.fact { background: rgba(255,255,255,.06); border: 1px solid rgba(255,255,255,.12); border-radius: 14px; padding: 1.1rem 1.2rem; transition: transform var(--t) var(--ease), background var(--t) var(--ease); }
.fact:hover { transform: translateY(-3px); background: rgba(255,255,255,.1); }
.fact strong { display: block; color: #fff; font-size: 1.5rem; font-weight: 800; letter-spacing: -.02em; }
.fact span { color: #AFC0CC; font-size: .9rem; }
.lead-program .checklist li { color: #D8E2EA; }
.lead-program .checklist svg { color: var(--orange); }

/* --------------------------------------------------------------------------
   SECTION: Market / unmet need cards
   -------------------------------------------------------------------------- */
.need-card { background: #fff; border: 1px solid var(--line); border-left: 4px solid var(--orange); border-radius: 14px; padding: 1.6rem; height: 100%;
   transition: transform var(--t) var(--ease), box-shadow var(--t) var(--ease); }
.need-card:hover { transform: translateY(-5px); box-shadow: var(--shadow-md); }
.need-card h3 { font-size: 1.12rem; margin-bottom: .4rem; }
.need-card p { margin-bottom: 0; font-size: .96rem; }
.need-card .placeholder { display: inline-block; margin-top: .6rem; font-size: .76rem; color: var(--orange-dark); background: var(--orange-soft); padding: .2rem .6rem; border-radius: 6px; font-weight: 600; }

/* --------------------------------------------------------------------------
   SECTION: Interactive tabs (theranostic story: Detect / Treat)
   -------------------------------------------------------------------------- */
.tabs { max-width: 980px; margin-inline: auto; }
.tabs__nav { display: inline-flex; gap: .3rem; padding: .35rem; background: var(--mist); border: 1px solid var(--line); border-radius: 999px; margin-bottom: 2rem; }
.tabs__btn { border: none; background: transparent; padding: .7rem 1.4rem; border-radius: 999px; font: inherit; font-weight: 700; color: var(--slate); cursor: pointer; transition: background var(--t) var(--ease), color var(--t) var(--ease); }
.tabs__btn[aria-selected="true"] { background: var(--orange); color: #fff; box-shadow: 0 6px 16px rgba(242,101,34,.3); }
.tabs__panel { display: none; animation: fadeUp .5s var(--ease); }
.tabs__panel.is-active { display: grid; }
@media (min-width: 880px) { .tabs__panel.is-active { grid-template-columns: 1fr 1fr; gap: clamp(28px,4vw,52px); align-items: center; } }
@keyframes fadeUp { from { opacity: 0; transform: translateY(16px); } to { opacity: 1; transform: none; } }

/* --------------------------------------------------------------------------
   SECTION: Process / vision timeline
   -------------------------------------------------------------------------- */
.timeline { display: grid; gap: 1.4rem; counter-reset: step; }
@media (min-width: 760px) { .timeline { grid-template-columns: repeat(4, 1fr); } }
.tl-step { position: relative; padding-top: 3.4rem; }
.tl-step::before { counter-increment: step; content: counter(step); position: absolute; top: 0; left: 0;
   width: 48px; height: 48px; border-radius: 50%; background: var(--orange-soft); color: var(--orange-dark);
   display: grid; place-items: center; font-weight: 800; font-size: 1.2rem; transition: transform var(--t) var(--ease); }
.tl-step:hover::before { transform: scale(1.1); background: var(--orange); color: #fff; }
.tl-step h3 { font-size: 1.05rem; margin-bottom: .3rem; }
.tl-step p { font-size: .92rem; margin-bottom: 0; }
@media (min-width: 760px) { .tl-step:not(:last-child)::after { content: ""; position: absolute; top: 23px; left: 56px; right: -16px; height: 2px;
   background: repeating-linear-gradient(90deg, var(--line) 0 6px, transparent 6px 12px); } }

/* --------------------------------------------------------------------------
   SECTION: Comparison table (theranostic category)
   -------------------------------------------------------------------------- */
.compare { width: 100%; border-collapse: collapse; background: #fff; border: 1px solid var(--line); border-radius: var(--radius); overflow: hidden; font-size: .96rem; }
.compare th, .compare td { text-align: left; padding: .9rem 1.1rem; border-bottom: 1px solid var(--line); }
.compare thead th { background: var(--navy-deep); color: #fff; font-size: .8rem; letter-spacing: .06em; text-transform: uppercase; }
.compare tbody tr:last-child td { border-bottom: none; }
.compare tbody tr.is-lead { background: var(--orange-soft); }
.compare tbody tr.is-lead td { font-weight: 600; color: var(--navy); }
.compare .status { font-weight: 700; }
.compare .status.approved { color: var(--ok); }
.compare .status.dev { color: var(--orange-dark); }
.compare .status.clinical { color: var(--slate); }
.compare-wrap { overflow-x: auto; -webkit-overflow-scrolling: touch; }

/* --------------------------------------------------------------------------
   SECTION: Copper accent band (Targeted Copper Theranostics)
   -------------------------------------------------------------------------- */
.band-copper { position: relative; overflow: hidden;
  background: linear-gradient(120deg, var(--copper-deep), var(--copper) 45%, var(--orange) 100%); color: #fff; }
.band-copper::after { content: ""; position: absolute; inset: 0; opacity: .5;
  background: radial-gradient(circle at 80% -10%, rgba(255,255,255,.25), transparent 55%); pointer-events: none; }
.band-copper h2, .band-copper h3 { color: #fff; }
.band-copper p { color: rgba(255,255,255,.92); }
.band-copper .eyebrow { color: #FCE4CF; }
.band-copper .eyebrow::before { background: #fff; }
.band-copper .stat strong { color: #fff; }
.band-copper .stat span { color: rgba(255,255,255,.9); }
.band-copper .stat { position: relative; }
.band-copper .stat:not(:last-child)::after { content: ""; }
.landscape-note { font-size: .8rem; color: rgba(255,255,255,.75); }

/* Compact 6-up landscape grid (smaller, more readable numbers) */
.stats--landscape { grid-template-columns: repeat(2, 1fr); gap: 1.4rem 1.2rem; }
@media (min-width: 760px) { .stats--landscape { grid-template-columns: repeat(3, 1fr); } }
.stats--landscape .stat { padding: .4rem .6rem; }
.stats--landscape .stat strong { font-size: clamp(1.5rem, 3vw, 2rem); }
.stats--landscape .stat span { font-size: .9rem; line-height: 1.4; }

/* Isotope chips */
.iso { display: inline-flex; align-items: center; gap: .4rem; padding: .25rem .7rem; border-radius: 999px;
  font-weight: 700; font-size: .82rem; letter-spacing: .02em; }
.iso--64 { background: rgba(184,115,51,.14); color: var(--copper-deep); border: 1px solid rgba(184,115,51,.35); }
.iso--67 { background: rgba(242,101,34,.12); color: var(--orange-dark); border: 1px solid rgba(242,101,34,.35); }

/* --------------------------------------------------------------------------
   SECTION: Status / availability badges
   -------------------------------------------------------------------------- */
.badge { display: inline-flex; align-items: center; gap: .45rem; padding: .35rem .8rem; border-radius: 999px;
  font-size: .78rem; font-weight: 700; letter-spacing: .04em; }
.badge--soon { background: #FFF3E9; color: var(--copper-deep); border: 1px solid #F2C9A3; }
.badge--invest { background: rgba(255,255,255,.1); color: #FCE4CF; border: 1px solid rgba(255,255,255,.25); }
.badge--soon::before { content: ""; width: 8px; height: 8px; border-radius: 50%; background: var(--copper); }

/* Inline availability note strip */
.avail-note { display: flex; flex-wrap: wrap; align-items: center; gap: .5rem 1rem; justify-content: center;
  background: var(--mist); border: 1px dashed var(--line); border-radius: 14px; padding: 1rem 1.4rem; }
.avail-note strong { color: var(--navy); }
.avail-note span { color: var(--slate); font-size: .95rem; }

/* --------------------------------------------------------------------------
   SECTION: Theranostic pairing (Cu-64 → Cu-67 matched pair)
   -------------------------------------------------------------------------- */
.pairing { display: grid; gap: 1rem; align-items: stretch; max-width: 820px; margin-inline: auto; }
@media (min-width: 720px) { .pairing { grid-template-columns: 1fr auto 1fr; } }
.pairing__card { background: #fff; border: 1px solid var(--line); border-radius: var(--radius-lg); padding: 1.6rem; text-align: center; transition: transform var(--t) var(--ease), box-shadow var(--t) var(--ease); }
.pairing__card:hover { transform: translateY(-4px); box-shadow: var(--shadow-md); }
.pairing__card .big { font-size: 1.8rem; font-weight: 800; letter-spacing: -.02em; }
.pairing__card.dx .big { color: var(--copper-deep); }
.pairing__card.tx .big { color: var(--orange-dark); }
.pairing__card .role { display: block; font-weight: 700; color: var(--navy); margin: .2rem 0; }
.pairing__card small { color: var(--slate); }
.pairing__link { display: grid; place-items: center; font-weight: 800; color: var(--copper); }
.pairing__link svg { width: 30px; height: 30px; }
@media (max-width: 719px) { .pairing__link svg { transform: rotate(90deg); } }

/* --------------------------------------------------------------------------
   SECTION: Clinical journey (decision points)
   -------------------------------------------------------------------------- */
.journey { display: grid; gap: 1.2rem; }
@media (min-width: 680px) { .journey { grid-template-columns: 1fr 1fr; } }
@media (min-width: 1000px) { .journey { grid-template-columns: repeat(4, 1fr); } }
.jcard { background: #fff; border: 1px solid var(--line); border-radius: var(--radius-lg); padding: 1.5rem 1.3rem; height: 100%;
  transition: transform var(--t) var(--ease), box-shadow var(--t) var(--ease), border-color var(--t) var(--ease); }
.jcard:hover { transform: translateY(-5px); box-shadow: var(--shadow-md); border-color: #F2C4A8; }
.jcard__num { font-size: .8rem; font-weight: 800; color: var(--orange); letter-spacing: .1em; }
.jcard h3 { font-size: 1.08rem; margin: .3rem 0 .7rem; }
.jcard .q { font-size: .92rem; color: var(--ink); margin-bottom: .7rem; }
.jcard .by { font-size: .8rem; color: var(--slate); border-top: 1px solid var(--line); padding-top: .6rem; }
.jcard .by b { color: var(--navy); font-weight: 700; }
.jcard.future { border-style: dashed; }
.jcard .future-tag { font-size: .68rem; font-weight: 800; letter-spacing: .12em; color: var(--copper-deep); background: #FFF3E9; padding: .15rem .5rem; border-radius: 6px; }

/* --------------------------------------------------------------------------
   SECTION: Path to clinic (regulatory milestones)
   -------------------------------------------------------------------------- */
.path { display: grid; gap: 1.2rem; counter-reset: pstep; }
@media (min-width: 760px) { .path { grid-template-columns: repeat(4, 1fr); } }
.pstep { position: relative; background: var(--mist); border: 1px solid var(--line); border-radius: var(--radius-lg); padding: 1.4rem; }
.pstep__status { font-size: .72rem; font-weight: 800; letter-spacing: .1em; text-transform: uppercase; }
.pstep.done   { border-left: 4px solid var(--ok); }       .pstep.done   .pstep__status { color: var(--ok); }
.pstep.active { border-left: 4px solid var(--orange); box-shadow: var(--shadow-sm); } .pstep.active .pstep__status { color: var(--orange-dark); }
.pstep.next   { border-left: 4px solid var(--copper); }   .pstep.next   .pstep__status { color: var(--copper-deep); }
.pstep.future { border-left: 4px solid var(--line); }     .pstep.future .pstep__status { color: var(--slate); }
.pstep h3 { font-size: 1.05rem; margin: .35rem 0 .4rem; }
.pstep p { font-size: .9rem; margin-bottom: 0; }

/* Magnetic-ish CTA shimmer */
.cta-band::after { content: ""; position: absolute; top: -50%; left: -60%; width: 50%; height: 200%;
   background: linear-gradient(90deg, transparent, rgba(255,255,255,.18), transparent); transform: skewX(-20deg);
   animation: shimmer 6s var(--ease) infinite; }
@keyframes shimmer { 0%, 100% { left: -60%; } 50% { left: 120%; } }